Relationship among genetic variants, obesity traits and asthma in the Taiwan Biobank.

Ying-Jhen HuangYi-Chi ChuChia-Wei ChenHsin-Chou YangHung-Ling HuangJing-Shiang HwangChun-Houh ChenTa-Chien Chan

Published in: BMJ open respiratory research (2023)

Obese phenotypes and obesity-related PRS are independent risk factors for having asthma in adults in the Taiwan Biobank. Overall, genetic risk for obesity increases the risk of asthma by affecting the obese phenotype.

Keyphrases

weight loss
metabolic syndrome
insulin resistance
type diabetes
chronic obstructive pulmonary disease
lung function
high fat diet induced
bariatric surgery
adipose tissue
weight gain
allergic rhinitis
genome wide
gene expression
skeletal muscle
dna methylation