Best Practices for Managing Patients with Unresectable Metastatic Gastric and Gastroesophageal Junction Cancer in Canada.
Stephanie L SnowDenise GabrielsonHoward LimMustapha TehféChristine Brezden-MasleyPublished in: Current oncology (Toronto, Ont.) (2024)
Gastric cancer (GC) is one of the most common types of cancer and is associated with relatively low survival rates. Despite its considerable burden, there is limited guidance for Canadian clinicians on the management of unresectable metastatic GC and gastroesophageal junction cancer (GEJC). Therefore, we aimed to discuss best practices and provide expert recommendations for patient management within the current Canadian unresectable GC and GEJC landscape. A multidisciplinary group of Canadian healthcare practitioners was assembled to develop expert recommendations via a working group. The often-rapid progression of unresectable GC and GEJC and the associated malnutrition have a significant impact on the patient's quality of life and ability to tolerate treatment. Hence, recommendations include early diagnosis, identification of relevant biomarkers to improve personalized treatment, and relevant support to manage comorbidities. A multidisciplinary approach including early access to registered dietitians, personal support networks, and palliative care services, is needed to optimize possible outcomes for patients. Where possible, patients with unresectable GC and GEJC would benefit from access to clinical trials and innovative treatments.
Keyphrases
- healthcare
- papillary thyroid
- locally advanced
- palliative care
- primary care
- liver metastases
- clinical practice
- squamous cell carcinoma
- clinical trial
- squamous cell
- small cell lung cancer
- gas chromatography
- end stage renal disease
- case report
- lymph node metastasis
- type diabetes
- chronic kidney disease
- mental health
- radiation therapy
- mass spectrometry
- insulin resistance
- risk factors
- childhood cancer
- peritoneal dialysis
- adipose tissue
- skeletal muscle
- young adults
- smoking cessation
- solid phase extraction