Red Sea Sponge Callyspongia siphonella Extract Induced Growth Inhibition and Apoptosis in Breast MCF-7 and Hepatic HepG-2 Cancer Cell Lines in 2D and 3D Cell Cultures.
Sana A FadilFadwa A AljoudAhmed R YonbawiAhmad J AlmalkiRawan H HareeriAbrar AshiMehal Atallah AlQriqriNada S BawazirHadeel H AlshangitiLamiaa A ShaalaDiaa T A YoussefFaris A AlkhilaiwiPublished in: OncoTargets and therapy (2024)
extract's ability to induce apoptosis, disrupt mitochondrial membrane potential, and arrest the cell cycle highlights its potential as a novel anticancer agent. Additional research is required to investigate the underlying mechanism by which this extract functions as a highly effective anticancer agent.