Paracetamol is a centrally acting analgesic using mechanisms located in the periaqueductal grey.

David André BarrièreFawzi BoumezbeurRomain DalmannRoberto CadedduDamien RichardJérémy PinguetLaurence DaulhacPhilippe SarretKevin WhittingstallMatthieu KellerSébastien MériauxAlain EschalierChristophe Mallet

Published in: British journal of pharmacology (2020)

The elucidation of the mechanism of action of paracetamol as an analgesic paves the way for pharmacological innovations to improve the pharmacopoeia of analgesic agents.

Keyphrases

neuropathic pain
anti inflammatory
spinal cord
anti inflammatory drugs
spinal cord injury
multiple sclerosis