Reference ranges of late-night salivary cortisol and cortisone measured by LC-MS/MS and accuracy for the diagnosis of Cushing's syndrome.

F PonzettoF SettanniMirko Parasiliti CaprinoF RumboloA NonnatoM RicciardoE AmanteG PrioloS VitaliL AnfossiE ArvatE GhigoR GiordanoG Mengozzi

Published in: Journal of endocrinological investigation (2020)

LC-MS/MS is the most accurate analytical platform for measuring salivary steroids. Obtained reference intervals are coherent with previously published data and diagnostic accuracy for diagnosis of overt hypercortisolism proved highly satisfactory.

Keyphrases

electronic health record
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systematic review
sleep quality
depressive symptoms
physical activity
single cell