Altered consciousness mediates the effect of hypernatremia, but not hyponatremia, on mortality among patients observed in the ICU.
Miguel Ángel Armengol de la HozSicheng HaoNathan H RainesLeo Anthony CeliPatricia Sánchez-GonzálezEnrique J GómezJohn DanzigerPublished in: Research square (2023)
Decreased consciousness mediates the association between increased mortality and hypernatremia, but not hyponatremia. Further studies are needed to explore neurologic mechanisms and directionality in this relationship.