Drug Repurposing and Personalized Treatment Strategies for Bipolar Disorder Using Transcriptomic.

Paola Rampelotto ZianiMarco Antônio de BastianiEllen ScottonPedro Henrique da RosaTainá SchonsGiovana MezzomoQuênia de CarvalhoFlávio KapczinskiAdriane R Rosa

Published in: Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) (2024)

Although preliminary, our data provides some insights regarding the biological patterns of BD into distinct mood states and potential therapeutic targets. The combined transcriptomic and bioinformatics strategy offers a route to advance drug discovery and personalized medicine by tapping into gene expression information.

Keyphrases

bipolar disorder
drug discovery
gene expression
major depressive disorder
single cell
rna seq
dna methylation
electronic health record
big data
health information
healthcare
depressive symptoms
artificial intelligence