Rebound-associated vertebral fractures after discontinuation of denosumab-from clinic and biomechanics.

Albrecht W PoppP K ZyssetK Lippuner

Published in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2015)

Studies are urgently needed to i) prove the underlying pathophysiological processes suggested above, ii) establish the predictive criteria exposing patients to an increased risk of RVF, and iii) determine appropriate treatment regimens to be applied in such patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
primary care
patient reported outcomes
combination therapy