Diet quality, dietary inflammatory index and body mass index as predictors of response to adjunctive N-acetylcysteine and mitochondrial agents in adults with bipolar disorder: A sub-study of a randomised placebo-controlled trial.
Melanie M AshtonOlivia M DeanWolfgang MarxMohammadreza MohebbiMichael BerkGin S MalhiChee H NgSue M CottonSeetal DoddJerome SarrisMalcolm HopwoodKeshav Faye-ChauhanYesul KimSarah R DashFelice N JackaNitin ShivappaJames R HebertAlyna TurnerPublished in: The Australian and New Zealand journal of psychiatry (2019)
These data support a possible association between diet (quality and inflammatory potential), body mass index and response to treatment for bipolar depression in the context of a nutraceutical trial. The results should be interpreted cautiously because of limitations, including numerous null findings, modest sample size and being secondary analyses.
Keyphrases
- bipolar disorder
- body mass index
- study protocol
- oxidative stress
- physical activity
- clinical trial
- double blind
- major depressive disorder
- weight loss
- open label
- phase iii
- depressive symptoms
- electronic health record
- quality improvement
- phase ii
- placebo controlled
- big data
- combination therapy
- replacement therapy
- deep learning
- data analysis