Oncologic outcomes of conservative treatment of atypical polypoid adenomyoma of the uterus: A two-center experience.
Paolo CasadioAntonio RaffoneAntonio TravaglinoDiego RaimondoBrunella ZizolfiGiulia ArmanoRoberto BuonaiutoLuigi InsabatoAntonio MolloRenato SeracchioliAttilio Di Spiezio SardoPublished in: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics (2022)
Conservative treatment appears to be a safe option in women with APA. The four-steps HR might be considered as the first-line conservative approach, while the addition of progestin does not seem to improve oncologic outcomes. However, the risk of progression to cancer highlights the need for a close and long-term follow up with ultrasonography and hysteroscopic biopsies, and for hysterectomy in patients not desiring pregnancy.
Keyphrases
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- magnetic resonance imaging
- ejection fraction
- prostate cancer
- rectal cancer
- type diabetes
- radical prostatectomy
- magnetic resonance
- metabolic syndrome
- computed tomography
- adipose tissue
- preterm birth
- pregnant women
- replacement therapy
- minimally invasive
- glycemic control