Fully automated measurement of plasma Aβ42/40 and p-tau181: Analytical robustness and concordance with cerebrospinal fluid profile along the Alzheimer's disease continuum in two independent cohorts.
Giovanni BellomoSherif BayoumyAlfredo MegaroAndrea TojaGiovanna NardiLorenzo GaetaniElena R BlujdeaFederico Paolini PaolettiAnna Lidia WojdaƚaDavide ChiasseriniWiesje Maria van der FlierInge M W VerberkCharlotte E TeunissenLucilla ParnettiPublished in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)
The identified cutoffs and probability-based models represent a significant step toward plasma AD molecular diagnosis.