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Extended autologous tracheal replacement by a novel pedicled thoraco-chondro-costal flap: a cadaveric proof of concept.

Kim de FrémicourtAlain WurtzDragos GeorgescuMatthieu Sarsam
Published in: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery (2024)
This model could represent a suitable autologous tracheal substitute, which is long, longitudinally flexible and eventually transversely rigid. No microsurgical vascular anastomoses are required. The technique is reproducible. The perichondria and periostea would regenerate vascularized neo-cartilaginous rings, potentially decreasing the need for long-term stenting. The inner pleural lining could potentially transform into ciliated epithelium as shown in previous preclinical studies.
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