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Inflammation-induced hypoparathyroidism triggered by combination immune checkpoint blockade for melanoma.

Beckey TrinhGuacimara Ortega SanchezPetra HerzigHeinz Laubli
Published in: Journal for immunotherapy of cancer (2019)
Our report demonstrates a rare endocrinopathy as a complication of combined PD-1 and CTLA-4 blockade. In addition, it provides evidence from the course of the disease that inflammation within the parathyroid gland is involved in the mechanism.
Keyphrases
  • oxidative stress
  • diabetic rats
  • high glucose
  • drug induced
  • endothelial cells