Inflammation-induced hypoparathyroidism triggered by combination immune checkpoint blockade for melanoma.
Beckey TrinhGuacimara Ortega SanchezPetra HerzigHeinz LaubliPublished in: Journal for immunotherapy of cancer (2019)
Our report demonstrates a rare endocrinopathy as a complication of combined PD-1 and CTLA-4 blockade. In addition, it provides evidence from the course of the disease that inflammation within the parathyroid gland is involved in the mechanism.