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p21-activated kinase 4 phosphorylates peroxisome proliferator-activated receptor Υ and suppresses skeletal muscle regeneration.

Yuancheng MaoChang Yeob HanLihua HaoIn Hyuk BangEun Ju BaeByung-Hyun Park
Published in: Journal of cachexia, sarcopenia and muscle (2021)
p1-activated kinase 4 is a new member of PPARγ kinase, and PAK4 inhibition may have a therapeutic role as an accelerant of muscle regeneration.
Keyphrases
  • skeletal muscle
  • stem cells
  • protein kinase
  • tyrosine kinase
  • insulin resistance
  • signaling pathway
  • type diabetes
  • wound healing
  • adipose tissue