Inflammatory breast cancer microenvironment repertoire based on DNA methylation data deconvolution reveals actionable targets to enhance the treatment efficacy.

Naiade CalancaFlavia Lima Costa FaldoniCristiano Pádua SouzaJeferson Santos SouzaBianca Elen de Souza AlvesMilena Botelho Pereira SoaresDeysi Viviana Tenazoa WongRoberto César Pereira Lima-JuniorFabio Albuquerque MarchiClaudia Aparecida RainhoSílvia Regina Rogatto

Published in: Journal of translational medicine (2024)

Our findings underscored cell subsets that distinguished patients with better survival and dysregulated markers potentially actionable through combinations of immunotherapy and epigenetic drugs.

Keyphrases

dna methylation
gene expression
genome wide
stem cells
single cell
electronic health record
cell therapy
machine learning
young adults
free survival
data analysis
deep learning
drug induced