Optical trapping assisted detection rate enhancement of single molecules on a nanopore optofluidic chip.
M RahmanM HarringtonM A StottY LiM J N SampadT D YuzvinskyA R HawkinsH Schmidt
Published in: Optica (2019)
We use optical trapping to deliver molecular targets to the vicinity of a nanopore for high-throughput single molecule analysis on an optofluidic chip. DNA detection rates increase over 80× to enable detection at attomolar concentrations.