Detection of Colorectal Cancer and Advanced Adenoma by Liquid Biopsy (Decalib Study): The ddPCR Challenge.
Audelaure JuncaGaëlle TachonCamille EvrardClaire VillalvaEric FrouinLucie Karayan-TaponDavid TougeronPublished in: Cancers (2020)
ctDNA had high sensitivity in detection of advanced mutated CRC but was unable to sensitively detect AA. ctDNA analysis was easy to perform and readily accepted by the population but requires combination with other circulating biomarkers before replacing iFOBT.