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A novel homozygous missense mutation (Met527Ile) in a consanguineous marriage family with inherited factor XII deficiency.

Meina LiuHuanhuan WangMiaomiao LinYanhui JinLihong YangMingshan Wang
Published in: Hematology (Amsterdam, Netherlands) (2021)
The novel mutation Met527Ile could potentially account for the reduced activity of FXII in this family.
Keyphrases
  • tyrosine kinase
  • intellectual disability
  • autism spectrum disorder
  • replacement therapy