Stem Cell Extracellular Vesicles as Anti-SARS-CoV-2 Immunomodulatory Therapeutics: A Systematic Review of Clinical and Preclinical Studies.
Sarah Hamdy AhmedMohamed Atef AlMoslemanyKenneth Whitaker WitwerAhmed Gamal TehamyNagwa El-BadriPublished in: Stem cell reviews and reports (2024)
Similar to their parental cells, stem cell EVs mediate lung tissue regeneration by targeting multiple pathways and thus hold promise in promoting the recovery of COVID-19 patients and improving the survival rate of severely affected patients.
Keyphrases
- stem cells
- sars cov
- end stage renal disease
- induced apoptosis
- newly diagnosed
- chronic kidney disease
- cell therapy
- prognostic factors
- small molecule
- cell cycle arrest
- respiratory syndrome coronavirus
- peritoneal dialysis
- bone marrow
- cell death
- signaling pathway
- mesenchymal stem cells
- endoplasmic reticulum stress
- oxidative stress
- coronavirus disease
- pi k akt