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Quantitative CT-derived vessel metrics in idiopathic pulmonary fibrosis: A structure-function study.

Joseph JacobMichael PiennChristian PayerMartin UrschlerMaria KokosiAnand DevarajAthol U WellsHorst Olschewski
Published in: Respirology (Carlton, Vic.) (2019)
Our study confirms previous observations of links between vessel volume and functional measures of disease severity in IPF using a new vessel quantitation tool. Additionally, the new tool shows independent linkages of normalized vessel volume and vessel heterogeneity with functional indices. Quantitative vessel metrics do not appear to reflect vasculopathic damage in IPF.
Keyphrases
  • idiopathic pulmonary fibrosis
  • computed tomography
  • oxidative stress
  • magnetic resonance imaging
  • mass spectrometry
  • single cell
  • systemic sclerosis
  • positron emission tomography