Proteomic profiling of idiopathic Parkinson's disease primary patient cells by SWATH-MS.

Stephen A Wood Peter G HainsArnaud MullerMelissa HillSusitha PremarathneMariyam MurtazaPhillip J Robinson George D Mellick Alex M Sykes

Published in: Proteomics. Clinical applications (2022)

This data from primary patient cells has uncovered a critical role of the UPR in patients with PD and may provide insight to the underlying cellular dysfunctions in these patients.

Keyphrases

induced apoptosis
cell cycle arrest
end stage renal disease
case report
chronic kidney disease
newly diagnosed
mass spectrometry
endoplasmic reticulum stress
prognostic factors
cell death
signaling pathway
oxidative stress
electronic health record
pi k akt