JCAD promotes arterial thrombosis through PI3K/Akt modulation: a translational study.
Luca LiberaleYustina M PuspitasariStefano MinistriniAlexander AkhmedovSimon KralerNicole R BonettiGeorgia BeerAna VukolicDario BongiovanniJiaying HanKilian KirmesIsabell BernlochnerJaroslav PelisekJürg H BeerZheng-Gen JinDaniela PedicinoGiovanna LiuzzoKonstantinos StellosFabrizio MontecuccoThomas F LüscherThomas F LüscherGiovanni G CamiciPublished in: European heart journal (2022)
JCAD promotes arterial thrombosis by modulating coagulation and fibrinolysis. Herein, reported translational data suggest JCAD as a potential therapeutic target for atherothrombosis.