Adverse Events Associated with Intranasal Sprays: An Analysis of the Food and Drug Administration Database and Literature Review.
Salma AhsanuddinRoman PovolotskiyRahma TayyabWissam NasserGregory L BarinskyJordon G GrubeBoris PaskhoverPublished in: The Annals of otology, rhinology, and laryngology (2021)
The AEs of dyspnea, anosmia, ageusia/dysgeusia, epistaxis, and headache are reported within the FAERS database for commonly prescribed INSs. When compared against the existing scientific literature, the clinical significance of this reporting tool from the FDA for these classes of medications remains unvalidated.