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Spectrophotometric azole and amphotericin B MIC readings against Aspergillus fumigatus sensu lato using the EUCAST 9.3.2 methodology. Are ≥90 and ≥95% fungal growth inhibition endpoints equally suitable?

Julia Serrano-LoboAna GómezPatricia MuñozPilar EscribanoJesus Vicente Guinea
Published in: Medical mycology (2022)
Spectrophotometrically obtained MIC readings using either ≥ 90% or ≥ 95% fungal growth inhibition endpoints and following the EUCAST methodology are suitable against A. fumigatus sensu stricto. However, the ≥ 95% fungal growth inhibition endpoint is preferred against cryptic species.
Keyphrases
  • cell wall
  • high resolution
  • mass spectrometry