Bone Morphogenic Protein for Upper Extremity Fractures: A Systematic Review.

Alexis B SandlerJohn P ScanaliatoSorana RaiciulescuLeon NestiJohn C Dunn

Published in: Hand (New York, N.Y.) (2021)

Most hand/wrist and humerus nonunions treated with BMP-7 and BMP-2 achieved union, with significant similarity among BMP-7 studies not observed in BMP-2 studies. Nonunions treated with BMP-7 have longer healing times yet similar complication rates compared with BMP-2. Overall, BMPs are an effective adjunct to fracture healing with acceptable complication profile.

Keyphrases

bone regeneration
mesenchymal stem cells
bone marrow
bone mineral density
case control
small molecule
body composition
hip fracture