The contribution of reinfection to annual rate of tuberculosis infection (ARI) and incidence of TB disease.
C Robert HorsburghYoungji JoBrooke E NicholsHelen E JenkinsColin A RussellLaura F WhitePublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)
Measured ARI underestimates true ARI as a result of heterogenous population mixing. The true force of infection in a community may be greater than previously appreciated. Hyperendemic communities likely contribute disproportionally to the global TB disease burden.