Association of gout and colorectal cancer in Taiwan: a nationwide population-based cohort study.

Jen-Pin ChuangJenq-Chang LeeTzeng-Horng LeuAtik Choirul HidajahYa-Hui ChangChung-Yi Li

Published in: BMJ open (2019)

Similar risks of CRC incidence were observed in patients with and without gout in Taiwan. Allopurinol and colchicine are commonly used as urate-lowering drug and anti-inflammation medication in Taiwan and had been shown to reduce the risk of CRC incidence. Thus, further pharmaco-epidemiological studies should be carried out to specifically assess the role of allopurinol in the relationship between gout and CRC.

Keyphrases

uric acid
risk factors
oxidative stress
adverse drug
metabolic syndrome
human health
risk assessment
climate change