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Ampicillin dosing in premature infants for early-onset sepsis: exposure-driven efficacy, safety, and stewardship.

Jennifer LeRachel Gottron GreenbergYoungJun YooReese H ClarkDaniel K BenjaminKanecia O ZimmermanMichael Cohen-WolkowiezKelly C Wadenull null
Published in: Journal of perinatology : official journal of the California Perinatal Association (2022)
For EOS in preterm infants, two ampicillin doses (50 mg/kg) provided optimal bactericidal exposures, while minimizing potential toxicity.
Keyphrases
  • early onset
  • preterm infants
  • late onset
  • low birth weight
  • acute kidney injury
  • air pollution
  • intensive care unit
  • septic shock
  • oxidative stress