In vitro chronic glycation induces AGEs accumulation reducing insulin-stimulated glucose uptake and increasing GLP1R in adipocytes.

Nino-Cristiano ChilelliAlessia FaggianFrancesca FavarettoGabriella MilanChiara CompagninFrancesca DassieSilvia BettiniMarco RoversoRoberta SeragliaAnnunziata LapollaRoberto Vettor

Published in: American journal of physiology. Endocrinology and metabolism (2021)

Intracellular AGEs accumulation increases RAGE and GLP1R and reduces glucose uptake in adipocytes.

Keyphrases

adipose tissue
blood glucose
type diabetes
glycemic control
high fat diet induced
reactive oxygen species
skeletal muscle
drug induced