PIEZO1 acts as a cancer suppressor by regulating the ROS/Wnt/β-catenin axis.

Haimei BoQi WuChaonan ZhuYang ZhengGuang ChengLihua Cui

Published in: Thoracic cancer (2024)

In summary, PIEZO1 acts as a cancer suppressor by regulating the ROS/Wnt/β-catenin axis, providing a new perspective on the role of mechanosensitive channel proteins in cancer.

Keyphrases

papillary thyroid
cell proliferation
squamous cell
stem cells
cell death
dna damage
epithelial mesenchymal transition
reactive oxygen species
signaling pathway