Evolution of transcriptional regulation of histidine metabolism in Gram-positive bacteria.

German A AshnievNatalia V SernovaAleksei E ShevkopliasIvan D RodionovIrina A RodionovaAlexey G VitreschakMikhail S GelfandDmitry A Rodionov

Published in: BMC genomics (2022)

The obtained distribution of the HisR transcription factor and two RNA-mediated regulatory mechanisms for histidine metabolism genes across over 600 species of Firmicutes is discussed from functional and evolutionary points of view.

Keyphrases

transcription factor
genome wide
genome wide identification
gram negative
dna binding
gene expression