Surface charge modulation of rifampicin-loaded PLA nanoparticles to improve antibiotic delivery in Staphylococcus aureus biofilms.
David Da CostaChloé Exbrayat-HéritierBasile RambaudSimon MegyRaphaël TerreuxBernard VerrierCharlotte PrimardPublished in: Journal of nanobiotechnology (2021)
Correlating the carrier retention capacity in biofilms with the treatment efficacy, positively charged rifampicin-loaded PLA nanoparticles are therefore proposed as an adapted and promising approach to improve antibiotic delivery in S. aureus biofilms.