Observational study of haemostatic dysfunction and bleeding in neonates with hypoxic-ischaemic encephalopathy.

Mitali A PakvasaAnne M WinklerShannon E HamrickCassandra D JosephsonRavi Mangal Patel

Published in: BMJ open (2017)

Among neonates with moderate-to-severe HIE, haemostatic dysfunction is prevalent and associated with an increased risk of bleeding and high transfusion burden. Further studies are needed to determine the appropriate transfusion approaches in this population to prevent bleeding.

Keyphrases

atrial fibrillation
cardiac surgery
early onset
oxidative stress
low birth weight
sickle cell disease
acute kidney injury
high intensity
preterm infants
drug induced