Facile preparation and conversion of 4,4,4-trifluorobut-2-yn-1-ones to aromatic and heteroaromatic compounds.
Takashi YamazakiYoh NakajimaMinato IidaTomoko Kawasaki-TakasukaPublished in: Beilstein journal of organic chemistry (2021)
The concise preparation of 4,4,4-trifluorobut-2-yn-1-ones by the oxidation of the readily accessible corresponding propargylic alcohols as well as their utilization as Michael acceptors for the construction of aromatic and heteroaromatic compounds are reported.