Apigetrin alleviates intervertebral disk degeneration by regulating nucleus pulposus cell autophagy.

Tao XuHongqi ZhaoJian LiXuan FangHua WuWei-Hua Hu

Published in: JOR spine (2024)

API inhibited degenerative phenotypes and promoted autophagy in vivo and in vitro IVDD models. Those suggested that API might be a potential drug or target for IVDD.

Keyphrases

cell death
endoplasmic reticulum stress
signaling pathway
oxidative stress
single cell
emergency department
human health
bone marrow
drug induced