Physiological system analysis of the kidney by high-temporal-resolution T 2 ∗ monitoring of an oxygenation step response.

Kaixuan ZhaoAndreas PohlmannQijian FengYingjie MeiGuixiang YangPeiwei YiQianjin FengWufang ChenLili ZhouEd X WuErdmann SeeligerThoralf NiendorfYanqiu Feng

Published in: Magnetic resonance in medicine (2020)

This study demonstrates the feasibility of monitoring the dynamic oxygenation response of renal tissues to a step-like oxygenation challenge using high-temporal-resolution T 2 ∗ mapping. Our results suggest that the implemented system analysis approach may help to unlock questions regarding regulation of renal oxygenation, with the ultimate goal of providing imaging means for diagnostics and therapy of renal diseases.

Keyphrases

blood flow
high resolution
gene expression
single molecule
mesenchymal stem cells
fluorescence imaging