Delayed mucosal anti-viral responses despite robust peripheral inflammation in fatal COVID-19.

Jasmin K SidhuMatthew K Siggins Felicity LiewClark D RussellAshley S S UruchurtuChristopher DavisLance C W TurtleShona C MooreHayley E HardwickWilna OosthuyzenEmma C Thomson Malcolm Gracie Semple John Kenneth Baillie Peter J M Openshaw Ryan S Thwaitesnull null

Published in: The Journal of infectious diseases (2023)

Defective early mucosal anti-viral responses anticipate fatal COVID-19 but are not associated with viral load. Early mucosal immune responses may define the trajectory of severe COVID-19.

Keyphrases

sars cov
coronavirus disease
immune response
respiratory syndrome coronavirus
ulcerative colitis
oxidative stress
early onset
dendritic cells
inflammatory response
chemotherapy induced