Polarization of HIV-1- and CMV-Specific IL-17-Producing T Cells among People with HIV under Antiretroviral Therapy with Cannabis and/or Cocaine Usage.
Fernanda de Oliveira Feitosa de CastroAdriana Oliveira GuilardeLuiz Carlos Silva SouzaRegyane Ferreira GuimarãesAna Joaquina Cohen Serique PereiraPedro Roosevelt Torres RomãoIrmtraut Araci Hoffmann PfrimerSimone Gonçalves da FonsecaPublished in: Pharmaceuticals (Basel, Switzerland) (2024)
Cannabis plus cocaine use increased HIV-specific IL-17 producing T-cells and cocaine use increased IL-17 CMV-specific CD8+ T-cell responses which could favor the inflammatory conditions associated with IL-17 overproduction.