The pro- and antineoplastic effects of deoxycholic acid in pancreatic adenocarcinoma cell models.

Szandra SchwarczPatrik KovácsTünde KovácsGyula UjlakiPetra NyergesKaren UrayPéter BaiEdit Mikó

Published in: Molecular biology reports (2023)

DCA induced antineoplastic effects in pancreatic adenocarcinoma cells by inhibiting EMT, reducing cancer stemness, and inducing oxidative/nitrosative stress and procarcinogenic effects such as hypermetabolic bioenergetics.

Keyphrases

epithelial mesenchymal transition
stem cells
induced apoptosis
squamous cell carcinoma
cell therapy
bone marrow
drug induced
cell proliferation
stress induced
endoplasmic reticulum stress
high glucose