Disposition Kinetics of Cathinone and its Metabolites after Oral Administration in Rats.
Fahad Y SabeiIbrahim KhardaliMohamed A Al-KasimEmad Sayed ShaheenMagbool OraibyAhmad AlamirBanji DavidSaeed AlshahraniAbdulmajeed M JaliMohammed AttafiMohammed Y AlbeishyIbraheem AttafiPublished in: Current drug metabolism (2024)
This study revealed a dynamic interplay between cathinone disposition kinetics and its impact on organ-specific metabolic profiles in rats. These results have significant implications for drug development, pharmacovigilance, and clinical practices involving cathinone. Investigating the correlation between the changes in biomarkers found in the brain and the levels of cathinone and cathine is essential for informed decision- making in medical practices and further research into the pharmacological properties of cathinone.