Do epigenetic clocks provide explanations for sex differences in lifespan? A cross-sectional twin study.

Anna KankaanpääAsko TolvanenPirkko SaikkonenAino HeikkinenEija K LaakkonenJaakko KaprioMiina OllikainenElina Sillanpää

Published in: The journals of gerontology. Series A, Biological sciences and medical sciences (2021)

Previously reported sex differences in lifespan are also evident in biological aging. Declining smoking prevalence among men is a plausible explanation for the narrowing of the difference in life expectancy between the sexes. Data generated by the epigenetic clocks may help in estimating the effects of lifestyle and environmental factors on aging and in predicting aging in future generations.

Keyphrases

dna methylation
gene expression
metabolic syndrome
risk factors
physical activity
cardiovascular disease
weight loss
big data
current status
deep learning