MiRNA-146a polymorphism increases the odds of malaria in pregnancy.
Welmoed van LoonPrabhanjan P GaiLutz HamannGeorge Bedu-AddoFrank P MockenhauptPublished in: Malaria journal (2019)
These results indicate that SNP rs2910164 G > C is associated with increased odds for P. falciparum infection in first-time pregnant women who are considered to lack sufficient acquired immune responses against pregnancy-specific strains of P. falciparum. These findings suggest that miRNA-146a is involved in protective malarial immunity, and specifically in the innate component.