Low-dose amitriptyline for irritable bowel syndrome (IBS): a qualitative study of patients' and GPs' views and experiences.

Emma Teasdale Hazel Anne EverittSarah AldersonAlexander FordJames HanneyMatthew ChaddockEmmajane WilliamsonHeather CookAmanda J FarrinCatherine FernandezElspeth A GuthrieSuzanne HartleyAmy HerbertDaniel HowdonDelia MuirSonia NewmanPei Loo OwMatthew J RiddChristopher M TaylorRuth ThorntonAlexandra Wright-HughesFelicity Bishop

Published in: The British journal of general practice : the journal of the Royal College of General Practitioners (2024)

Patients and GPs felt the potential benefits from trying low-dose amitriptyline for IBS outweighed their concerns. When offering low-dose amitriptyline for IBS, GPs could address patient concerns about taking an antidepressant for IBS, highlighting the low and flexible dosage and other potential benefits of amitriptyline such as improved sleep.

Keyphrases

irritable bowel syndrome
low dose
high dose
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
major depressive disorder
mental health
prognostic factors
depressive symptoms
patient reported