Link Between Obsessive-Compulsive Disorder and ApoE Gene Polymorphisms.

The ApoE gene polymorphism profile and age of onset in OCD patients may play critical roles in the development process of neurodegenerative characteristics of the disease. The small number of cases and the inability to perform brain imaging in patients to detect the neurodegenerative link in OCD are limitations of our study. In this respect, we suggest conduction of further studies with a greater number of patients who will also undergo brain imaging studies. In addition, OCD patients have other genes associated with neurodegenerative diseases that can be screened.