HBV RNA profiles in chronic hepatitis B patients under different disease phases and anti-viral therapy.
Loey Lung-Yi MakGavin ClohertyDanny Ka-Ho WongJeffrey GerschWai-Kay SetoJames Yan-Yue FungMan-Fung YuenPublished in: Hepatology (Baltimore, Md.) (2020)
HBV RNA showed distinct and corresponding profile in HBV patients in different disease phases. HBV RNA and HBcrAg could be used to monitor residual transcriptional activities in patients with HBsAg seroclearance. NA led to reduction of serum HBV RNA. Monitoring of viral activities can still be achieved in patients with undetectable HBV DNA by serum HBV RNA.
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