Effect of Hyaluronic Acid/Trehalose in Two Different Formulations on Signs and Symptoms in Patients with Moderate to Severe Dry Eye Disease.

Klemens FondiPiotr A WozniakDoreen Schmidl Ahmed M Bata Katarzyna J WitkowskaAlina Popa-CherecheanuLeopold Schmetterer Gerhard Garhöfer

Published in: Journal of ophthalmology (2018)

Our results show improvement in signs and symptoms of DED in both groups. While instillation of HTC-gel resulted in a lower instillation frequency, both formulations of trehalose showed good clinical efficacy. This trial is registered with NCT02980913.

Keyphrases

hyaluronic acid
sleep quality
clinical trial
study protocol
phase iii
early onset
high intensity
phase ii
physical activity
drug induced