A simple immunoassay for extracellular vesicle liquid biopsy in microliters of non-processed plasma.

Carmen Campos-SilvaYaiza Cáceres-MartellEstela Sánchez-HerreroAmaia SandúaAlexandra Beneitez-MartínezÁlvaro GonzálezMariano ProvencioAtocha RomeroRicardo Jara-AcevedoMaría Yáñez-MóMar Vales-Gomez

Published in: Journal of nanobiotechnology (2022)

This optimized high throughput, easy to automate, technology allows screening of large numbers of patients to phenotype tumour markers in circulating EVs, breaking barriers for the validation of proposed EV biomarkers and the discovery of new ones.

Keyphrases

high throughput
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
small molecule
peritoneal dialysis
ultrasound guided
patient reported outcomes