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Combined anticoagulant and antiplatelet therapy is associated with an improved outcome in hospitalised patients with COVID-19: a propensity matched cohort study.

Kamal MatliNibal ChamounAya FaresVictor ZibaraSoad Al-OstaRabih NasrallahPascale SalamehJacques MokhbatGeorges Ghanem
Published in: Open heart (2021)
The use of combined anticoagulant and antiplatelet agents or TAC alone in hospitalised patients with COVID-19 was associated with a better outcome in comparison to PAC alone without an increase in the risk of major and minor bleeds. Sufficiently powered randomised controlled trials are needed to further evaluate the safety and efficacy of combining antiplatelet and anticoagulants agents or using TAC in the management of patients with COVID-19 infection.
Keyphrases
  • antiplatelet therapy
  • acute coronary syndrome
  • percutaneous coronary intervention
  • atrial fibrillation
  • venous thromboembolism
  • community acquired pneumonia
  • coronary artery disease
  • clinical evaluation