Four-Month Rifapentine Regimens with or without Moxifloxacin for Tuberculosis.
Susan E DormanPayam NahidEkaterina V KurbatovaPatrick P J PhillipsKia BryantKelly E DooleyMelissa EngleStefan V GoldbergHa T T PhanJames HakimJohn L JohnsonMadeleine LourensNeil A MartinsonGrace MuzanyiKim NarunskySandy NeretteNhung V NguyenThuong H PhamSamuel PierreAnne E PurfieldWadzanai SamanekaRadojka M SavicIan SanneNigel A ScottJustin ShenjeErin SizemoreAndrew VernonZiyaad WajaMarc WeinerSusan SwindellsRichard E Chaissonnull nullnull nullPublished in: The New England journal of medicine (2021)
The efficacy of a 4-month rifapentine-based regimen containing moxifloxacin was noninferior to the standard 6-month regimen in the treatment of tuberculosis. (Funded by the Centers for Disease Control and Prevention and others; Study 31/A5349 ClinicalTrials.gov number, NCT02410772.).