The High Relevance of 21-Deoxycortisol, (Androstenedione + 17α-Hydroxyprogesterone)/Cortisol, and 11-Deoxycortisol/17α-Hydroxyprogesterone for Newborn Screening of 21-Hydroxylase Deficiency.
Kazuhiro WatanabeAtsumi Tsuji-HosokawaAtsuko HashimotoKaoru KonishiNobuyuki IshigeHarumi YajimaAkito SutaniHisae NakataniMaki GauKei TakasawaToshihiro TajimaTomonobu HasegawaTomohiro MorioKenichi KashimadaPublished in: The Journal of clinical endocrinology and metabolism (2022)
Our study demonstrated the high relevance of 21DOF, (4AD + 17αOHP)/F, and 11DOF/17αOHP, rather than 17αOHP, for 21OHD screening.